Alzheimer’s disease

January 26th, 2010 | Under: Anticonvulsants, Articles »

AD (Alzheimer’s disease) is a brain disease that causes memory impairment, then go disturbances in reasoning, language, perception and planning. Scientists suppose Alzheimer’s disease is caused by an increased production of beta-amyloid protein in the brain which results in the death of nerve cells.

The risk of getting Alzheimer’s disease rises greatly after 70 and might affect 50% of people over 85. Nevertheless Alzheimer’s disease is not at all a usual aging part and it is actually not a thing that will inevitably occur in life. A lot of people live over one hundred years and they never have Alzheimer’s disease.

The common trigger of Alzheimer’s disease is age. Generally when people age, the Alzheimer’s disease frequency increases. 10 per cent of individuals over 65 and 50 per cent of people over 85 suffer from Alzheimer’s disease. If no new medications are developed to reduce the risks of getting Alzheimer’s disease, the quantity of people with AD in the US is forecasted to reach 14 million by 2050.

Genetic risk conditions play a crucial part in developing Alzheimer’s disease. Most often people can develop Alzheimer’s disease after 70 years old. But 2-5 per cent individuals can develop AD in the 4th- 5th life decade which is in their 40s and 50s. Half of the early onset people have so to say inherited gene mutations attributed to their AD. Besides the kids of a person with early onset AD that possesses 1 of the gene mutations is at a 50 per cent possibility to develop Alzheimer’s disease.

Genetic risk is also present in late onset episodes. A common gene form found on the 19th chromosome is usually attributed to late onset AD. In most cases of Alzheimer’s disease no particular genetic risks have been identified.

Other risks for developing AD are hypertension (high blood pressure), diabetes, coronary artery disease, and also high cholesterol levels. People who have only completed 8 or even less years of education are at high risk of developing Alzheimer’s disease as well. These conditions raise the possibility of AD, but they do not at all imply that Alzheimer’s disease is sure to strike people who are within these risk groups.

All people suffering from Down syndrome are likely to develop brain changes of Alzheimer’s disease by the age of 40.

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